Ole OLSEN,Phil TAN,Dong XIA,David JELLYMAN,Brian KOVACEVICH,Bill BRADY,Blair RENSHAW,Zeren GAO,Yi ZHU
申请号：
US16615109
公开号：
US20200157217A1
申请日:
2018.06.22
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The applications provides the anti-CD3 monoclonal antibodies, antigen-binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to active CD3+ T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
