The invention is related to the use of a composition of fenofibrate containing micronized fenofibrate, a surfactant and a binding cellulose derivative as a solubilization adjuvant, said composition containing an amount of fenofibrate greater than or equal to 60% by weight, for the preparation of a medicament for treating hypertriglyceridemias, hypercholesterolemias or hyperlipidemias while reducing the food effect on the bioävailability of fenofibrate. The invention is also related to an immediate release composition in the form of granules comprising : (a) a neutral core； (b) an active layer, wich surrounds the core； and (c)an outer layer； wherein said active layer comprises micronized fenofibrate, a surfactant and a binding cellulose derivative； and wherein said composition has a dissolution profile of less than 10% at 5 minutes and more than 80% at 20 minutes according to the European Pharmacopoeia in a dissolution medium constituted by water with 0.025 M sodium lauryl sulfate.
