Smrcina, Martin,Francis, Robert S.,Le, Tieu-Binh,Thorpe, David S.,Clemens, Jennifer,John, Stanly,Wire, William,Caulfield, Thomas J.,Ramos, Antonio D.,Rosse, Gerard,Freed, Brian S.,Pedgrift, Brian,Zhao
申请号：
AU2008259804
公开号：
AU2008259804B2
申请日:
2008.06.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention relates to A compound of the formula Ia wherein in any ofits stereoisomers forms or a mixture of stereoisomeric forms in any ratio, ora physiologically acceptable salt thereof, wherein the substituents are asdescribed herein. The inventive compounds have CXCR5 inhibitory activity areparticularly useful in treating or preventing various inflammatory diseases,such as rheumatoid arthritis, multiple sclerosis, lupus, Crohn's Disease,associated with the modulation of the human CXCR5 receptor.
