A sterilizable composite bag or pouch at a temperature of at least about 125℃ includes a first sheet comprising a gas-permeable but bacteria-impermeable polyolefin material, a second sheet comprising a first layer comprising a polyolefin with a density of less than 0.94 g/cm3 disposed between a second layer and a third layer comprising a high density polyolefin and having a density of at least 0.94 g/cm3, with the first sheet and the second sheet being locally thermally welded to one another to form a bag or pouch defining a cavity suitable for holding an article. A method includes thermally bonding such layers to form a plurality of bags and subjecting the plurality of bags to an autoclave steam sterilization process, wherein each second sheet thereafter remains pinhole-free and substantially impermeable to bacteria.本發明揭示一種在温度至少約125℃之可滅菌複合袋或套袋,其包括:一第一片材,其包含一透氣但細菌不能穿透的聚烯烴材料;一第二片材,其包含一第一層,該第一層包含一具有密度小於0.94g /cm3且置於一第二層及一第三層間的聚烯烴,該第二及第三層包含一高密度聚烯烴且具有密度至少為0.94 g/cm3,該第一片材及該第二片材為彼此局部熱熔接以形成界定一內穴的袋或套袋,其中該內穴適於容納一物件。本發明另揭示一種方法,其包括:熱黏接此等層以形成多數個袋;及將該多數個袋進行高壓釜(autoclave)蒸氣滅菌作用製程,其中每一第二片材在之後維持成無針孔且細菌實質上不能穿透。30...袋或套袋32、34、36...密封
