R. Blake Pepinsky,Richelle Sopko,Joshua Mugford,Andreas Lehmann,Joseph W. Arndt,Nels E. Pederson,Brenda K. Minesinger
申请号：
US16063423
公开号：
US20200270335A1
申请日:
2016.12.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Proteins containing a DKK2 polypeptide or a fragment or variant thereof are described. These proteins contain human serum albumin sequences and/or include substitutions in the DKK2 polypeptide that decrease heparin binding. These proteins are useful in the treatment of disorders such as acute kidney injury and fibrosis.
