PROBLEM TO BE SOLVED: To provide a means for ameliorating digestive tract disorder or the like which is the adverse effect of loxoprofen.SOLUTION: A pharmaceutical composition is provided, which contains loxoprofen or its salt and tranexamic acid or its salt. Preferably, loxoprofen or its salt is a loxoprofen sodium hydrate.COPYRIGHT: (C)2010,JPO&INPIT【課題】ロキソプロフェンの副作用である消化管障害の軽減等の方法を提供する。【解決手段】ロキソプロフェン又はその塩とトラネキサム酸又はその塩とを含有する医薬組成物。【選択図】なし