CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET);INIS BIOTECH LLC
发明人:
Javier Alberto Ramirez,Flavia Mariana Michelini,Lydia Raquel Galagovsky,Alejandro Berra,Laura Edith Alche
申请号:
US14365893
公开号:
US20150094288A1
申请日:
2012.12.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of treating a solid tumor in a mammal by inhibiting angiogenesis, including administering to the mammal which has a solid tumor selected from the group consisting of breast carcinoma, lung carcinoma, prostate carcinoma, colon carcinoma, ovarian carcinoma, neuroblastoma, central nervous system tumor, multiform glioblastoma and melanoma; a composition including brassinosteroids of general formula (I)wherein can be a single or double bond and the configurations of carbon atoms C22 and C23 respectively linked to the substituents HO are S for both carbon atoms and a pharmaceutically acceptable additive.