FIELD: chemistry.SUBSTANCE: invention relates to obtaining biocompatible magnetic nano-particles and can be applied for therapeutic purposes, in particular, for fighting cancer. Method of obtaining nano-particles, including iron oxide and silicon-containing casing and having value of specific absorption rate (SAR) 10-40 W per g of Fe with field strength 4 kA/m and frequency of alternating magnetic field 100 kHz, contains the following stages: A1) preparation of composition of at least one iron-containing compound in at least one organic solvent； B1) heating of composition to temperature in range from 50°C to temperature 50°C lower than temperature of reaction of iron-containing compound according to stage C1 for minimal period 10 minutes； C1) heating composition to temperature between 200°C and 400°C； D1) purification of obtained particles； E1) suspending purified nano-particles in water or water acid solution； F1) addition of surface-active compound to water solution, obtained according to stage E1)； G1) processing of water solution according to stage F1) by ultrasound； H1) purification of water dispersion of particles, obtained according to stage G1)； I1) obtaining dispersion of particles according to stage H1) in mixture of solvent from water and water-mixable solvent； J1) addition of alkoxysilane into dispersion of particles in mixture of solvent according to stage I1)； and K1) purification of particles.EFFECT: invention makes it possible to obtain biocompatible magnetic particles with high value of specific absorption rate (SAR).42 cl, 3 dwg, 9 exИзобретение относится к получению биосовместимых магнитных наночастиц и может быть использовано для терапевтических целей, в частности для борьбы с раком. Способ получения наночастиц, включающих оксид железа и кремнийсодержащую оболочку и имеющих значение удельного коэффициента поглощения (SAR) 10-40 Вт на г Fe при напряженности поля 4 кА/м и частоте переменного магнитного поля 100 кГц, содержит следующие стадии: А1)
