Provided are novel compounds that bind to FKBP12 or pharmaceutically acceptable salts thereof, as well as new therapeutics useful in the prevention or treatment of alopecia which comprise those compounds or pharmaceutically acceptable salts thereof. Specifically, compounds represented by formula (1) [where R 1 represents either the following formula (2) or (3)] or pharmaceutically acceptable salts thereof are provided.Predmetni pronalazak se odnosi na nova jedinjenja koja se vezuju za FKBP12 ili na njihove farmaceutski prihvatljive soli, kao i na sredstva za prevenciju ili tretman alopecije koja sadrže takva nova jedinjenja ili farmaceutski prihvatljive soli takvih jedinjenja kao aktivni sastojak.
