Joseph Charles Salamone,Kelly Xiaoyu Chen Leung,Ann Beal Salamone,Katelyn Elizabeth Reilly
申请号:
US14511912
公开号:
US09592280B2
申请日:
2014.10.10
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of enzymes. The amylases (α-, β-, γ-amylase) are noted for the cleavage of the α-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found that α-amylase is effective in the debridement of devitalized tissue.