The invention relates to a textile implant comprising at least one thread having a polymeric core and a polymeric sheath which surrounds the polymeric core at least partly, wherein the sheath includes a composition comprising at least one silica-supported antimicrobial active, and also to a method of forming the textile implant. The invention further relates to a tubular medical device, particularly in the form of an extrudate, having an at least two-layered construction comprising an inner layer surrounding a tubular lumen and an outer layer surrounding the inner layer, wherein the inner layer and/or the outer layer include a composition comprising at least one silica-supported antimicrobial active, and also to a method of forming the tubular medical device.