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RASAGILINE ORALLY DISINTEGRATING COMPOSITIONS
专利权人:
Shulamit Patashnik
发明人:
Shulamit Patashnik,Daniella Licht,Adrian Gilbert
申请号:
US14458410
公开号:
US20150031774A1
申请日:
2014.08.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, and particles having a non-filamentous microstructure of at least two sugar alcohols. This invention also provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, a mixture of a disintegrant, a flow agent and particles having a non-filamentous microstructure of at least two sugar alcohols, a supplemental sugar alcohol, a supplemental flow agent, and a supplemental disintegrant. This invention further provides a method of treating a subject afflicted with Parkinsons disease comprising administering to the subject a therapeutically effective amount of the solid pharmaceutical composition, thereby treating the subject. Finally, this invention provides a process of making such solid pharmaceutical compositions.
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