THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
Edward Paul HASTY,Dmitri Nickolaevich IVANOV
申请号:
US16756705
公开号:
US20200253913A1
申请日:
2018.10.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided here are therapeutically effective pharmaceutical compositions containing one or more TREX2 inhibitors, and more specifically methods of administering TREX2 inhibitors to increase the effectiveness of a chemotherapeutic agent. Also provided here are methods of identifying agents that inhibit the exonuclease activity of TREX2.