A polyp trap may comprise an upper and lower housing, and a porous separating disk. The upper housing may be domed with a top view window for viewing tissue retained by the disk. The disk is seated in the lower housing and may be held in place by the upper housing, when the upper housing is coupled to the lower housing. The upper and lower housings are coupled using interlocking flange members extending from the walls of the upper housing and the lower housing. In one example, the upper housing holds the disk in place by engaging a post, which doubles as a handle for removing tissue from the disk and transferring the tissue to a storage container or bag. Alternatively, a peripheral portion of the disk or both of these may be used for securing the disk in the trap. Mating posts in the lower housing may engage guide holes in the disk to further secure the disk in the trap.
