The disclosure provides a method, an electronic apparatus, and a computer readable medium of constructing a classifier for disease detection. The method includes the following steps. A codebook of representative features is constructed based on a plurality of disease-irrelevant data. Transfer-learned disease features are extracted from disease-relevant bio-signals according to the codebook without any medical domain knowledge, where both the disease-irrelevant data and the disease-relevant bio-signals are time-series data. Supervised learning is performed based on the transfer-learned disease features to train the classifier for disease detection.
