NUCLEIC ACID MOLECULE CAPABLE OF BINDING TO HMGB1, AND USE THEREOF

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专利权人:

发明人:

申请号：

EP10799934.4

公开号：

EP2455469A1

申请日:

2010.07.16

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Aa nucleic acid molecule that can bind to HMGB1 protein and applications thereof are provided. A nucleic acid molecule having a dissociation constant for HMGB1 protein of 5 × 10-7 or less can be used as the nucleic acid molecule that can bind to HMGB1 protein. The HMGB1 binding nucleic acid molecule can bind to HMGB1 protein that is known to be a cause of diseases such as cancer and inflammation, and it is therefore possible to obtain an effect to prevent and an effect to treat such diseases by allowing the HMGB1 binding nucleic acid molecule to bind to HMGB1 protein in a living body

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中国工程科技知识中心

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http://www.ckcest.cn/home/