A surgical stapler instrument with an auxiliary tissue compression means for stapling a tissue with a plurality of staples comprises; a handle, an elongate shaft having a proximal end and a distal end extending therefrom, operatively coupled to said handle, and an elongate end effector having a proximal end attached to said distal end of said shaft, a distal end extending therefrom; said end effector comprising a first jaw member having an anvil thereon and a second jaw member, opposing said first jaw member, having a staple cartridge housing a plurality of staples therein and a cartridge bay configured to releasably receive said staple cartridge, and a compression bladder disposed between cartridge bay and said staple cartridge or driving at least a portion of said staple cartridge toward said first jaw member; said jaw members movable with respect to each other from an open position, wherein said jaw members are spaced apart, to a closed position wherein said jaw members are in close approximation to one another.