To provide a method of malignant tumor extinction by supersonic irradiation and a method of enhancing a medicament effect on a malignant tumor and bacterial infection.SOLUTION: A biological portion where a malignant tumor or bacteria exist is irradiated with sonic beams having opposite phases so as to overlap. A portion where the sonic beams having opposite phases overlap vibrates waving with large amplitude in a sonic advancing direction, and can cut off a tumor vessel if increasing a sonic intensity. Further, an anticancer agent is spread and impregnated well to malignant cells existing at the portion where the sonic beams having opposite phases overlap.SELECTED DRAWING: None【課題】超音波照射による悪性腫瘍死滅方法、また悪性腫瘍、細菌感染の薬物効果増強方法を提供する。【解決手段】悪性腫瘍や細菌が存在する生体部位に、位相が正反対の音波ビームを重なるように照射する。位相が正反対の音波ビームが重なっている部分は、音波の進行方向に振幅が大きく波打って振動し、音波強度を上げれば腫瘍血管を切断できる。また、音波の位相が正反対の音波ビームの重ね合なる部分にある悪性細胞に抗癌剤がよく拡散して浸透する。【選択図】なし