POMYTKIN IGOR ANATOLIEVICH,포미트킨, 이고르 아나토리예비치,PETROPAVLOV IGOR ARTUROVIC,페트로파블로브, 이고르 아르투로빅
申请号：
KR1020147008245
公开号：
KR1020140066209A
申请日:
2008.11.07
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
The present invention relates to pharmaceutical, dermatological, cosmeceutical, or cosmetic compositions comprising (a) interleukin-1 family members consisting of interleukin-1 alpha, interleukin-1 family member 5 (delta), interleukin-1 family member 6 (epsilon), interleukin-1 family member 7 (zeta), interleukin-1 family member 8 (eta), interleukin-1 family member 9, interleukin-1 family member 10 (theta), and interleukin-18； (b) a peptide of the general formula (I): Tyr-X1-X2-Phle-X3-X4-Y, wherein X1 is Gly, L-Ala or D-Ala； X2 is Gly, L-Ala or D-Ala； X3 is absent or independently Leu, Met, Iie, or Val； X4 is absent or independently Ala, Asp, Asn, Glu, Gln, Pro, Arg, Gly, Lys, Thr, or Ser； Y is absent or a sequence of 1 to 5 amino acid residues； and acceptable carriers or diluents.본 발명은 인터루킨-1 알파, 식 Tyr-D-Ala-Gly-Phe-Leu-Asp의 펩티드, 및 피부학적으로 허용가능한 희석제 또는 담체를 포함하는 화장료 조성물을 제공한다. 본 발명의 조성물은 특히 피부 노화의 조짐 감소에 유용하다.
