RAHDAR, MEGHDAD,PRAKASH, THAZHA P.,SWAYZE, ERIC E.,BENNETT, FRANK C.
申请号:
CA2990699
公开号:
CA2990699A1
申请日:
2016.06.29
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present disclosure provides compounds comprising modified oligonucleotides for use in CRISPR. In certain embodiments, such modified oligonucleotides provide improved properties of crRNA. In cetain embodiments, such modified oligonucleotides provide improved properties of scrRNA.