BENZYLAMINE Compounds, inhibitors of plasma kallikrein； Pharmaceutical Composition and its use for the treatment of impaired Visual Acuity, Diabetic Retinopathy, macular edema, diabetic cardiomyopathy, hypertension, cancer, among others
EVANS, DAVID MICHAEL,DAVIE, REBECCA LOUISE,EDWARDS, HANNAH JOY,ROOKER, DAVID PHILIP
申请号：
CL2014000032
公开号：
CL2014000032A1
申请日:
2014.01.07
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The present invention provides compounds of formula (I): compositions comprising such compounds； the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated)； and methods of treating patients with such compounds； wherein R1 to R9 are as defined herein.<；p>；LA PRESENTE INVENCIÓ；N SE REFIERE A UN COMPUESTO DE FÓ；RMULA (1), TAUTÓ；MEROS, ESTEREOISÓ；MEROS (INCLUYENDO<；br />；ENANTIÓ；MEROS, DIASTEROLSÓ；MEROS Y MEZCLAS RACÉ；MLCAS Y ESCALÉ；MICAS DE LOS MISMOS), SALES ACEPTABLES<；br />；FARMACÉ；UTICAMENTE Y SOLVATOS DEL MISMO； UNA COMPOSICIÓ；N FARMACÉ；UTICA QUE LO COMPRENDE Y SU USO PARA EL<；br />；TRATAMIENTO DE AGUDEZA VISUAL DETERIORADA, RETINOPATÍ；A DIABÉ；TICA, EDEMA MACULAR DIABÉ；TICO, HIPOTENSIÓ；N,<；br />；CARDIOMIOPATÍ；A, CÁ；NCER, ENTRE OTROS.<；/p>；
