This invention is directed to the use of noribogaine, noribogaine derivative, or a pharmaceutically acceptable salt and/or solvate thereof at a dosage that provides a therapeutic serum concentration for treating a disease or disorder as described herein in a patient.本發明係關於降伊波加因(noribogaine)、降伊波加因衍生物或其醫藥學上可接受之鹽及/或溶劑合物在提供治療血清濃度之劑量用於治療患者如本文所述之疾病或病症的用途。