The present invention relates to methods of administering compositions comprising a progesterone receptor antagonist for use in treating estrogen-dependent conditions. The invention is also directed to methods for treating pain associated with endometriosis. The compositions may be administered to females with endometriosis as well as to females undergoing estrogen and/or selective estrogen receptor modulator (SERM) therapy. In certain embodiments, the invention provides a method for suppressing endometrial proliferation.Ovaj izum se odnosi na metode uzimanja jedinjenja uključujući antagonist receptora progesterona za upotrebu u liječenju estrogen-zavisnog stanja . Izum je takođe usmjeren na postupke tretiranja bolova koji se dovode u vezu s endometriozom. Jedinjenja se mogu davati ženama s endometriozom kao i ženama koje su izvrgnute terapiji estrogenom i/ili selektivnim modulatorima receptora estrogena (SERM). U nekim svojim oblicima, izum daje postupak za potiskivanje endometrijske proliferacije.