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Compounds and methods for modulating interaction between proteins and target nucleic acids
专利权人:
Adrian R. Krainer;Frank Rigo;Yimin Hua;C. Frank Bennett
发明人:
Frank Rigo,C. Frank Bennett,Adrian R. Krainer,Yimin Hua
申请号:
US13703322
公开号:
US09518259B2
申请日:
2011.06.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided herein are antisense compounds and methods for recruiting one or more non-cleaving protein to a target nucleic acid in a cell. In certain instances such recruitment of a non-cleaving protein alters the function or activity of the target nucleic acid. In certain such instances, the target nucleic acid a pre-mRNA and the recruitment of the non-cleaving protein results in a change in splicing of the pre-mRNA.
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