This invention provides an oral interface mainly including a connecting channel, a collapsible chamber and a non-collapsible structure disposed inside the collapsible chamber. The connecting channel communicates between the collapsible chamber and a negative source. When a negative pressure environment is generated inside the collapsible chamber via being pumped by the negative source, the non-collapsible structure supports the collapsible chamber so that there are fluid channels formed inside the collapsible chamber. The air inside a user’s oral cavity can be pumped out via the fluid channels and the connecting channel. A negative pressure environment is hence formed inside the user’s oral cavity.本發明提供一種口部介面裝置,主要包括一連接管、一可塌陷腔體及一非可塌陷結構。該連接管一端係欲連通於一負壓源及另一端連通於該可塌陷腔體。該可塌陷腔體的另一對端係呈一開孔狀及該非可塌陷結構設置於該可塌陷腔體的至少一內壁面。當該可塌陷腔體透過該負壓源在其腔體內產生一負壓環境時,該非可塌陷結構支撐該可塌陷腔體,使該可塌陷腔體在塌陷時內部形成有流體通道,並且一使用者口腔內的空氣經由該可塌陷腔體內部流體通道及該連接管被抽離出來,以使該使用者口腔產生一負壓環境。100‧‧‧口部介面裝置110‧‧‧連接管120‧‧‧可塌陷腔體130‧‧‧非可塌陷結構140‧‧‧開孔端