Tomasz Popek;Kishore Patel;Valery Alakhov;Grzegorz Pietrzynski
发明人:
Tomasz Popek,Kishore Patel,Valery Alakhov,Grzegorz Pietrzynski
申请号：
US12711979
公开号：
US08436032B2
申请日:
2010.02.24
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is directed to pharmaceutical compositions comprising: (a) bendamustine, (b) a charged cyclopolysaccharide, and (c) a stabilizing agent having a charge opposite to that of the cyclopolysaccharide. Such composition provides unexpectedly desirable stability in reactive environments such as plasma, coupled with unexpectedly desirable anticancer activity. Such compositions are suitable for injection or infusion into patients in need for treatment with bendamustine.
