INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY;NATIONAL DEVELOPMENT INSTITUTE OF KOREAN MEDICINE
发明人:
LEE, SYNG OOK,이승욱,LEE, HYO SEON,이효선,SHIN, HEUNG MOOK,신흥묵,KIM, SOO HYUN,김수현,LEE, SYNG OOKKR,LEE, HYO SEONKR,SHIN, HEUNG MOOKKR,KIM, SOO HYUNKR
申请号：
KR1020160113280
公开号：
KR1018214980000B1
申请日:
2016.09.02
申请国别(地区):
KR
年份:
2018
代理人:
摘要：
The present invention relates to a pharmaceutical composition for preventing or treating cancer diseases comprising broussochalcone A as an active ingredient, and it was confirmed that the broussochalcone A inhibits the activity of NR4A1 in cancer cells overexpressing NR4A1 to effectively inhibit cancer cell growth and induce apoptosis, and thus the composition comprising the broussochalcone A as the active ingredient can be provided as a pharmaceutical composition for preventing or treating cancer diseases and health food.본 발명은 브루소찰콘 A를 유효성분으로 함유하는 암질환 예방 또는 치료용 약학조성물에 관한 것으로, 상기 브루소찰콘 A는 NR4A1가 과발현된 암세포에서 NR4A1의 활성을 억제하여 암세포 성장 억제 및 세포사멸을 효과적으로 유도하는 것으로 확인됨에 따라, 브루소찰콘 A를 유효성분으로 함유하는 조성물은 암질환 예방 또는 치료용 약학조성물 및 건강식품으로 제공될 수 있다.
