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Influenza treatment drugs, characterized by: an endocrine inhibitor based on cap and an antiretroviral agent
专利权人:
SHIONOGI and CO.; LTD.
发明人:
SHISHIDOJP, Takao,NOSHI, Takeshi,YAMAMOTO, Atsuko,KITANO, Mitsutaka
申请号:
PE2018001110
公开号:
PE20181516A1
申请日:
2016.12.14
申请国别(地区):
PE
年份:
2018
代理人:
摘要:
It refers to a drug with the following characteristics: (a) a compound represented by a formula (I): a salt or solution with acceptable efficacy, in which p is h or a group of people to form a profarmaco; A1 is cr1ar1b, s or O; A2 is cr2ar2b, s or O; A3 is cr3ar3b, s or O; A4 is cr4ar4b, s or O; heterogenous amount in the atom. 1. A ring composed of ammonium nitrate near A1, A2, A3, A4 and A1 and carbon atoms near A4; R1a, r1b, R2A, r2b, R3a, R3b, R4A and r4b are h, halogen, tar, etc.; h, halogen, tar, etc.; h, halogen, tar, etc.; R1a, r1b, R2A, r2b, R3a, R3b, R4A and r4b are h, halogen, tar, etc.; R1a, r4b, r4b and r4b are h, tar, etc;N is any integer from 1 to 2, R1 is a formula compound (II),It is combined with (b) compounds with antivirus activity.Se refiere a un medicamento caracterizado porque (A) un compuesto representado por la formula (I): su sal farmaceuticamente aceptable, o un solvato del mismo, en la que P es H o un grupo para formar un profarmaco; A1 es CR1AR1B, S u O; A2 es CR2AR2B, S u O; A3 es CR3AR3B, S u O; A4 es CR4AR4B, S u O; el numero de heteroatomos entre los atomos que constituyen el anillo que consiste en A1, A2, A3, A4, atomo de nitrogeno adyacente a A1 y atomo de carbono adyacente A4 es 1 o 2; R1A, R1B, R2A, R2B, R3A, R3B, R4A y R4B son H, halogeno, alquilo, entre otros; son H, halogeno, alquilo, entre otros; son H, halogeno, alquilo, entre otros; n es cualquier numero entero de 1 a 2 y R1 es un compuesto de formula (II), se combina con (B) compuestos que tienen una actividad antigripal.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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