Gary E. Striker;Calogera M. Simonaro;Helen Vlassara;Edward H. Schuchman
发明人:
Edward H. Schuchman,Calogera M. Simonaro,Gary E. Striker,Helen Vlassara
申请号：
US14128411
公开号：
US20140205584A1
申请日:
2012.06.20
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to methods of treating a subject with a lysosomal disorder, by administering an agent for enzyme replacement therapy and an agent for anti-TNF-α therapy； by administering a pentosan polysulfate therapy； or by administering a substrate reduction therapy and an anti-TNF-α therapy. The invention further relates to a method of reducing inflammatory cytokines in a subject with a lysosomal disorder that is being treated by enzyme replacement therapy, by administering an agent for anti-TNF-α therapy.
