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Novel 3-hydroxyisothiazole 1-oxide derivative
专利权人:
持田製薬株式会社
发明人:
大河内 宗隆
申请号:
JP2013239340
公开号:
JP5905437B2
申请日:
2013.11.19
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
[Object] To provide a GPR40 activating agent containing, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the compound or the salt, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases. [Means of Solving the Problem] A compound of Formula (I): (where p is 0 to 4; j is 0 to 2; k is 0 to 1; a ring A is an aryl group, a heterocyclic group, a cycroalkyl group, a cycroalkenyl group, a spirocyclic group; a ring B is an aryl group, a heteroaryl group; X is O or -NMR 7 -; and R 1 to R 7 and L are specific groups), a salt of the compound, or a solvate of the compound or the salt.
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