An orthopedic brace for the correct anatomical locking and support of the backbone includes a semi-rigid dorsal structure with a vertical extension, closed inside a casing, having a conformation corresponding to a backbone, allowing the trend thereof to be followed and the spine itself to be supported. The lower part of the dorsal structure is connected to a lumbar strap that can be fastened at the front to a constraint in turn connected to the upper part of the dorsal structure. The dorsal structure and the lumbar strap are associated with each other through a rotary junction configured for retaining and mutual rotation on one plane of the dorsal structure relative to the lumbar strap.