KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION;고려대학교산학협력단
发明人:
SHIN, Min-Jeong,신민정,KIM, Hyeon Soo,김현수,JEONG, Inhyeok,정인혁,YOO, Eun Hye,유은혜,CHUNG, Ji Hyung,정지형
申请号:
KRKR2019/012929
公开号:
WO2020/071795A1
申请日:
2019.10.02
申请国别(地区):
KR
年份:
2020
代理人:
摘要:
The present invention pertains to an anticancer composition containing IF1 (ATPase inhibitory factor 1). The IF1 (ATPase inhibitory factor 1) according to the present invention has the effect of releasing extracellular ATP, induces cytotoxicity in various cancer cells and exhibits anticancer efficacy, and is thus very useful as an active ingredient of a powerful anticancer agent.La présente invention concerne une composition anticancéreuse contenant de l'IF1 (facteur inhibiteur de l'ATPase 1). L'IF1 (facteur inhibiteur de l'ATPase 1) selon la présente invention a pour effet de libérer l'ATP extracellulaire, induit une cytotoxicité dans diverses cellules cancéreuses et présente une efficacité anticancéreuse, et est donc très utile en tant que principe actif d'un puissant agent anticancéreux.본 발명은 IF1 (ATPase inhibitory factor 1)을 함유하는 항암용 조성물에 관한 것이다. 본 발명에 따른 IF1 (ATPase inhibitory factor 1)은 세포외 ATP 방출 효과를 가지며, 다양한 암세포에서 세포독성을 나타내어 항암 효능을 발휘하므로, 강력한 항암제의 활성성분으로 매우 유용하다.