Dana-Farber Cancer Institute, Inc.;The Scripps Research Institute
发明人:
Bruce M. Spiegelman,Jonathan Z Long,Hua Lin,Theodore Kamenecka,Patrick Griffin
申请号:
US16768211
公开号:
US20200317613A1
申请日:
2018.11.29
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Uncoupling of respiration is a well-recognized process that increases respiration and heat production in cells. Provided herein are chemical uncouplers of respiration that are compounds of Formula (I). Also provided are methods for preventing or treating metabolic disorders and modulating metabolic processes using compound of Formula (I).