經取代哌啶－二氫噻吩并嘧啶农业专利-农业专业知识服务系统

发明人:: POUZET, PASCALE,帕斯凯尔　保杰特,帕斯凱爾　保傑特,ANDERSKEWITZ, RALF,拉弗　安德斯凯维兹,拉弗　安德斯凱維茲,DOLLINGER, HORST,侯斯特　道陵格,FIEGEN, DENNIS,丹尼斯　菲振,FOX, THOMAS,汤姆士　福克斯,湯姆士　福克斯,GOEGGEL, ROLF,罗夫　高杰尔,羅夫　高傑爾,HOENKE, C,帕斯凯尔保杰特,帕斯凱爾保傑特,拉弗安德斯凯维兹,拉弗安德斯凱維茲,侯斯特道陵格,丹尼斯菲振,汤姆士福克斯,湯姆士福克斯,罗夫高杰尔,羅夫高傑爾

摘要：: The invention relates to new piperidino-dihydrothienopyrimidines of formula1, as well as pharmacologically acceptable salts thereof,whereinXis SO or SO2, but preferably SO, and wherein R1, R2, R3and R4may have the meanings given in claim 1, as well as pharmaceutical compositions which contain these compounds.These new piperidino-dihydrothienopyrimidines are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers.本發明係關於新穎式1哌啶基－二氫噻吩并嘧啶，以及其藥理學上可接受之鹽，其中X為SO或SO2，但較佳為SO，且其中R1,R2,R3及R4可具有請求項1中所予之意義，以及含有此等化合物之醫藥組合物。此等新穎哌啶基－二氫噻吩并嘧啶係適用於治療呼吸道或胃腸病苦或疾病，關節、皮膚或眼睛之炎性疾病，末梢或中樞神經系統之疾病或癌症。