PROBLEM TO BE SOLVED: To provide a regeneration treatment apparatus and operating method thereof which enable an increase in the cell viability in cell transplantation and achieve a sufficient repair of the organ.SOLUTION: The regeneration treatment apparatus comprises a heart rate detector 5 which detects a heart rate of a patient, a memory part 10 which stores a heart rate prior to stimulation, stimulating electrodes which stimulate a vagus nerve that controls an organ having transplanted cells, and a control unit 7 which controls an intensity of a stimulation signal to be output from the stimulating electrodes to the vagus nerve so that the heart rate of the patient detected by the heart rate detector 5 is decreased by 5 to 20% as compared to the state prior to the stimulation.COPYRIGHT: (C)2009,JPO&INPIT【課題】細胞移植における細胞の生着力を増大させて、臓器の十分な修復を図る。【解決手段】患者の心拍数を検出する心拍数検出部5と、刺激開始前の心拍数を記憶する記憶部10と、細胞が移植された臓器を支配している迷走神経に刺激を与える刺激用電極と、心拍数検出部5により検出された患者の心拍数が、刺激開始前の状態に対して5~20%減少するように刺激用電極から迷走神経に出力する刺激信号の強度を制御する制御部7とを備える再生治療装置を提供する。【選択図】図2