Compositions for chimeric antigen receptor T cell therapy and uses thereof

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专利权人:

Massachusetts Institute of Technology

发明人:

IRVINE, Darrell, J.,MA, Leyuan

申请号：

AU2018336791

公开号：

AU2018336791A1

申请日:

2018.09.19

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The disclosure describes amphiphilic ligand conjugates comprising a chimeric antigen receptor (CAR) ligand, a lipid (diacyl lipid), a linker (hydrophilic polymers, hydrophilic amino acids, polysaccharides), compositions and methods of using the constructs are claimed, for example, to stimulate proliferation of CAR expressing cells.

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