The present disclosure relates to a semipermeable membrane. The present disclosure aims to provide a semipermeable membrane having tolerance against a decrease over time in substance permeability. The present disclosure provides a semipermeable membrane (10) containing a resin. The permeation rate of albumin in the semipermeable membrane (10) is no lower than 30%. The albumin adsorption amount obtained when the semipermeable membrane (10) measuring 1 cm on each side is immersed in a 0.1% albumin solution for 90 minutes is no greater than 10 µg/cm2. The water permeation amount obtained when water is sucked through the semipermeable membrane (10) at a negative pressure of 3±0.2 kPa is expressed by no smaller than 1,000 L/(m2·hour). The semipermeable membrane (10) can isolate a cell from an external environment.