Novel porphyrin derivatives, especially chlorin and / or bacteriochlorin, and their application in photodynamic therapy

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专利权人:

ウニベルシダデ デ コインブラ

发明人:

ミゲンス，ペレイラ マリア,アルナウト モレイラ，ルイス ギルヘルメ,フォルモシンホ シモンイス，セバスティアンオ ジョセ,モンテイロ，カルロス,ミゲンス,ペレイラ マリア,アルナウト モレイラ,ルイス ギルヘルメ,フォルモシンホ シモンイス,セバスティアンオ ジョセ,モンテイロ,カルロス

申请号：

JP2007540608

公开号：

JP5226317B2

申请日:

2005.11.10

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The invention relates to derivatives of porphyrin, particularly chlorins and/or bacteriochlorins, which can be used in photodynamic therapy. According to the formulas of the invention, X1, X2, X3, X4, X5, X6, X7, X8, which may be identical or different, each represent halogen atoms or hydrogen atoms. R1, R2, R3, R4, which may be identical or different, are each selected from the following groups: -OH, amino acids, -OR and -NHR and/or a chlorine atom, wherein R is an alkyl group having between 1 and 12 carbon atoms. The invention also relates to an anticancer and/or antiviral and/or antimicrobial medicament for human or animal use, which contains one or more compounds as the main active ingredient.

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