A pulsed laser system has a cavity-dumped frequency-shift (fs) oscillator (11) as a source of radiation (15). Beam devices shape (21), guide (22), deflect (23) or focus (24) beams and can be programmed. Mounting devices position /fix (32) material (90) to be handled. The cavity-dumped fs oscillator supplies laser pulses of 100 nJ to 100 mu J pulse energy, preferably 1 mu J. An independent claim is also included for a method for applying a laser beam of frequency-shift (fs) pulses in a cavity-dumped fs oscillator to organic material and tissue in order to use photo-disruption for disintegrating the cohesion of the material in the focal point of a laser beam.