The present invention belongs to the technical field of chemicals and discloses the application in the preparation of substituted quinolone derivatives or pharmaceutically acceptable salts thereof, prodrug molecules and pharmaceutical compositions thereof and anticancer agents, Derivatives thereof, salts thereof, prodrug molecules and pharmaceutical compositions thereof can be used as protein kinase inhibitors, effectively suppress the activity of AXL protein kinase and inhibit the growth, migration, and invasion of various tumor cells It can be efficiently inhibited. The substituted quinolone derivative or a pharmaceutically acceptable salt thereof has a structural formula shown in the following formula (I). The substituted quinolone derivatives or their pharmaceutically acceptable salts, prodrug molecules, pharmaceutical compositions according to the present invention can effectively inhibit the activity of protein kinases such as AXL and can also inhibit the growth of various tumor cells , Migration, and invasion, can be used for preparing antitumor agents, and can be used for preparing drugs for treating hyperproliferative disorders such as human and other mammalian tumors in particular .Selection drawing None
