WU SHENG-JIUN,MALIA THOMAS,MERCKEN MARC,VANDERMEEREN MARC,JANECKI DARIUSZ,LIU XUESONG,MURDOCK MELISSA,ALDERFER CHRISTOPHER
申请号：
NZ62626912
公开号：
NZ626269A
申请日:
2012.12.19
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Anti-PHF-tau antibodies wherein the antigen binding site of the VH comprises heavy chain complementarity determining regions (CDRs) SSWMG (SEQ ID NO: 7), DILPGSGGTNYNERFKG(SEQ ID NO: 8) and SYYDYDRFAN(SEQ ID NO: 9) or SYAMS(SEQ ID NO: 13), SISKGGNTYYPNSVKG(SEQ ID NO: 14) and GWGDYGWFAY(SEQ ID NO: 15) and the antigen binding site of the VL comprises light chain CDRs RSSESLLHSNGNTYLY(SEQ ID NO: 10 ), RMSNLAS(SEQ ID NO: 11) and MQYLEYPLT(SEQ ID NO: 12) or KASQDINRYLN(SEQ ID NO: 16), ANRLLD(SEQ ID NO: 17) and LQYDEFPLT(SEQ ID NO: 18).
