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PROCÉDÉ DE FABRICATION D'AGRÉGAT DE CELLULES CONTENANT DES TISSUS PITUITAIRES, ET AGRÉGAT DE CELLULES
专利权人:
Sumitomo Chemical Company; Limited
发明人:
申请号:
EP18881914.8
公开号:
EP3715450A1
申请日:
2018.11.22
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention aims to provide a method for efficiently producing a cell mass containing pituitary tissue from pluripotent stem cells. A method for producing a cell mass containing pituitary tissue, including the following steps (1) and (2):(1) a first step of suspension-culturing pluripotent stem cells to form a cell aggregate in the presence of a Wnt signal transduction pathway inhibiting substance,(2) a second step of suspension-culturing the aggregate obtained in the first step in the presence of a BMP signal transduction pathway activating substance and a Sonic hedgehog signal transduction pathway activating substance, thereby obtaining a cell mass comprising pituitary tissue.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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