INC.;UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION
发明人:
Alicja Copik,Vijay Reddy,Jeremiah Oyer
申请号:
US16672949
公开号:
US20200138908A1
申请日:
2019.11.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The application provides new compositions and methods for stimulating the production of natural killer (NK) cells in a subject. NK cells can be selectively expanded with a combination of stimulating ligands. Methods and compositions for the administration of stimulatory ligands modified to self-insert into tumor cells, thereby stimulating an increase in the number of NK cells in proximity to a tumor, are also described.