An exemplary stapedius reflex measurement safety system includes a stimulation management facility configured to direct a cochlear implant system to apply an electrical stimulus to an auditory pathway of a patient and a detection facility configured to determine that a change in acoustic immittance that occurs as the electrical stimulus is being applied by the cochlear implant system is likely representative of a rise time phase associated with an occurrence of a stapedius reflex within the patient. The stimulation management facility is further configured to direct, in response to the determination, the cochlear implant system to cease applying the electrical stimulus.