A tissue anchor or tack that is reinforced by a three-dimensional mesh for improved strength and structural support for the tissue tack. The three-dimensional mesh may be formed of a bioabsorbable or non-absorbable material and may comprise fibers which are weaved, laced, crosslinked, or glued together, for example. The three-dimensional mesh may be also provided by molding a suitable pre-polymeric compound into a shape which directly provides the desired mesh structure. The three-dimensional mesh is preferably molded into the tissue tack. The mesh reinforced tissue tack is preferably cannulated and has a tack shaped configuration.