USE OF POLYOLS TO OBTAIN STABLE POLYMORPHOUS FORMS OF RIFAXIMIN

• 收藏
• 分享

专利权人:

ALFA WASSERMANN S.p.A.

发明人:

MAFFEI Paola,MAFFEI Paola,BACHETTI Milena,BACHETTI Milena,BOTTONI Giuseppe,BOTTONI Giuseppe,VISCOMI Giuseppe Claudio,VISCOMI Giuseppe Claudio

申请号：

SI200731941

公开号：

SI2059232T1

申请日:

2007.07.31

申请国别(地区):

SI

年份:

2017

代理人:

摘要：

Polyols stabilize polymorphous form of rifaximin, in particular the ² form. When polyols having at least two hydroxy groups are added to rifaximin powder, polymorph ² is stable and remains stable in time independently from the environment humidity. In this invention a method to prepare formulations constituted by pure and stable polymorphous forms able to give a pharmaceutical product is described.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/