PANCOOK, James David,ROWLINSON, Scott William,STANCATO, Louis Frank
申请号：
CR20190539
公开号：
CR20190539A
申请日:
2018.04.20
申请国别(地区):
CR
年份:
2020
代理人:
摘要：
The current invention involves innovative changes in human BMP7 proteins. The invention includes carriers and stellar cells for the transmission and production of nucleic acid sequences of proteins. It also introduces the treatment of cancer, cartilage damage and degeneration, pain or cure caused by osteoarthritis. The sea. Invention related to a new variety of human BMP7 protein. The invention embodies vectors and host cells for the promotion of nuclear acid sequences encoming said proteins and the production there. Also disclosed are methods for the treatment of cancer，Cartilage Damage and Degradation，Pain Associated with Osteoarthritis，or Bone Healing.La presente invención se refiere a variantes novedosas de la proteína BMP7 humana. La invención incorpora vectores y células hospederas para la propagación de secuencias de ácido nucleico que codifican las proteínas y la producción de las mismas. También se describen métodos para el tratamiento de cáncer, daño y degeneración de cartílago, dolor asociado con osteoartritis, o curación ósea.The present invention relates to novel variants of human BMP7 protein. The invention embodies vectors and host cells for the propagation of nucleic acid sequences encoding said proteins and the production thereof. Also disclosed are methods for the treatment of cancer, cartilage damage and degeneration, pain associated with osteoarthritis, or bone healing.
