UNIVERSITY OF MARYLAND EASTERN SHORE;THOMAS JEFFERSON UNIVERSITY;UNIVERSITY OF MARYLAND
发明人:
Vincent C. O. Njar,Lalji K. Gediya,Puranik Purushottamachar,Abhijit Godbole,Andrew Kwegyir-Afful,Tadas Vasaitis
申请号：
US14794416
公开号：
US09439912B2
申请日:
2015.07.08
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present disclosure provides the design and synthesis of novel steroidal compounds that cause down-regulation of the androgen receptor (AR), both full length and splice variant. The compounds are potential agents for the treatment of all forms of prostate cancer and other diseases that depend on functional AR.
