Christopher Malcuit,Linda Lemieux,William Holmes,Pedro Huertas,Lucy Vilner
申请号：
US14254833
公开号：
US20150086512A1
申请日:
2014.04.16
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides improved methods for producing RPE cells from human embryonic stem cells or from other human pluripotent stem cells. The invention also relates to human retinal pigmented epithelial cells derived from human embryonic stem cells or other human multipotent or pluripotent stem cells. hRPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The hRPE cells described herein are useful for treating retinal degenerative diseases.
