9- [4- (3-Chloro-2-fluoro-phenylamino) -7-methoxy-quinazolin-6-yloxy] -1,4-diaza-spiro [5.5] undecan-5-onedimaleate, Use as a medicine and method for producing the same
The present invention relates to a compound of formula (I), which has valuable pharmacological properties, particularly an inhibiting effect on signal transduction mediated by tyrosine kinases, processes for stereoselectively preparing these compounds, particularly pharmaceutical formulations suitable for inhalation and their use for the treatment of diseases, particularly tumoral diseases, benign prostatic hyperplasia and diseases of the lungs and airways.本発明は、有益な薬理学的特性、特にチロシンキナーゼによって媒介されるシグナル伝達に及ぼす阻害効果を有する下記式(I)の化合物、前記化合物、特に吸入に適した医薬製剤の立体選択的製造方法、並びに病気、特に腫瘍性疾患、良性前立腺肥大症、及び肺や呼吸器の疾患を治療するためのそれらの使用に関する。【化1】(I)【選択図】なし